Injectable Peptide Supplement Selank 5mg/vial Nootropic Drug for Increasing

Injectable Peptide Supplement Selank 5mg/vial Nootropic Drug for Increasing Energy

Description:

Selank is a nootropic, anxiolytic peptide based drug developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. Selank is a heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. It is a synthetic analogue of a human tetrapeptide tuftsin.

Selank effects:

Experimental and clinical studies showed the following pharmaclogical effects of Selank:

improvement of learning and memory processes (reference, reference)
increased sensory attention
increased curiosity
increased mental clarity
restoration of balance of serotonergic and noradrenergic brain system activity (reference)
anti-anxiety - inhibition of anxiety (reference)
antiviral activity with no negative effects (reference)
psychostimulant, anti-asthenic - increased mental energy (reference)
stabilization of mood and overall feeling of wellbeing
reversal of anhedonia (restoring the feeling of pleasure)
potential restoration of catecholaminergic system functions after damage due to drug abuse reference

Selanks Mechanism of Action:

Selank appears to exert its effects through dopamine, serotonin and norepinephrine modulation while also having potent effects on the immune system.

A rodent study showed a 0.3mg/kg injection of Selank was able to increase norepinephrine and serotonin in various regions of the brain, including the hippocampus and frontal cortex

A similar study noted an increase of serotonin metabolism in the hypothalamus 30-120 minutes after 0.3mg/kg injection into rodents

A third study demonstrated selank was able to prevent hypoxia induced decreases in serotonin and norepinephrine, which preserved normal behavior

Interestingly, when compared directly to tuftsin, the endogenous peptide that selank is based upon, selank would appear superior. A rodent study which sought to block the synthesis of serotonin with p-chlorophenylalanine saw enhanced serotonin levels with selank administration but no result with tuftsin. Clearly the PGP “tail” addition to the molecule somehow enhances its effects.

Selank dosage:

Its always best to start with a low dose and gradually build up to your individual comfortable levels.

Research has shown that intranasal (nasal spray) delivery of Selank is rougly 9 times more effective than injectable. This is attributed to some of it being able to bypass the blood-brain barrier.

1. Selank as nasal spray or drops (more effective):
duration: from 10 days to as long as needed
dosage: between 400 mcg - 9 mg of Selank per day
daily frequency:total daily dosage split into 3 doses throughout the day

2. Injectable Selank use (less effective):
duration: from 10 days to as long as needed
dosage: between 250 mcg - 3 mg per day
frequency of injection:1 injection per day for low dose, 2 injections for higher dose (divided between morning and late afternoon injection)

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Injectable Peptide Supplement Selank 5mg/vial Nootropic Drug for Increasing Images