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Home>Products>Legal Anabolic Steroids>CAS 62-44-2 Legal Anabolic Steroids White Powder Phenacetin Pain Killer Medicine

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  • CAS 62-44-2 Legal Anabolic Steroids White Powder Phenacetin Pain Killer Medicine
  • CAS 62-44-2 Legal Anabolic Steroids White Powder Phenacetin Pain Killer Medicine
  • CAS 62-44-2 Legal Anabolic Steroids White Powder Phenacetin Pain Killer Medicine
  • CAS 62-44-2 Legal Anabolic Steroids White Powder Phenacetin Pain Killer Medicine

CAS 62-44-2 Legal Anabolic Steroids White Powder Phenacetin Pain Killer Medicine

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  • 62-44-2

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Product Details

CAS number: 62-44-2 MF: C10H13NO2 MW: 179.22
Appearance: white powder Purity: ≥98% Usage: pain killer

Product Description

Phenacetin Pain Killer Medicine CAS 62-44-2 over 99% Purity White Powder

 

Basic information:

 

Chemical name: Phenacetin
MF: C10H13NO2
MW: 179.22
CAS: 62-44-2
Appearance: white powder
Purity: over 99%

 

Uses:

 

Phenacetin was widely used until the third quarter of the twentieth century, often in the form of an "A.P.C.," or "aspirin-phenacetin-caffeine" compound analgesic, as a remedy for fever and pain. An early formulation (1919) was Vincents APC in Australia.

 

But the U.S. Food and Drug Administration ordered the withdrawal of drugs containing phenacetin in November of 1983, owing to its carcinogenic and kidney-damaging properties (Federal Register of October 5, 1983 (48 FR 45466)). It was also banned in India.As a result, some branded, and previously phenacetin-based, preparations continued to be sold, but with the phenacetin replaced by safer alternatives. A popular brand of phenacetin was Roches Saridon, which was reformulated in 1983 to contain propyphenazone, paracetamol and caffeine. Coricidin was also reformulated without phenacetin. Paracetamol is a metabolite of phenacetin with similar analgesic and antipyretic effects, but the new formulation has not been found to have phenacetins carcinogenicity.

Phenacetin is now being used as a cutting agent to adulterate cocaine in the UK and Canada, owing to the similar physical features of the two drugs.

 

Due to its low cost, phenacetin is used for research into the physical and refractive properties of crystals. It is an ideal compound for this type of research.

 

Mechanism of action:

 

Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treat rheumatoid arthritis (subacute type) and intercostal neuralgia.

 

It is metabolized in the body to paracetamol (acetaminophen), which is also a clinically relevant analgesic.


Safety:

 

Phenacetin, and products containing phenacetin, have been shown in an animal model to have the side effect and after-effect of carcinogenesis. In humans, many case reports have implicated products containing phenacetin in urothelial neoplasms, especially urothelial carcinoma of the renal pelvis. In one prospective series, phenacetin was associated with an increased risk of death due to urologic or renal diseases, death due to cancers, and death due to cardiovascular diseases.In addition, people with glucose-6-phosphate dehydrogenase deficiency may experience acute hemolysis, or dissolution of blood cells, while taking this drug. Acute hemolysis is possible in the case of patients who develop an IgM response to phenacetin leading to immune complexes that bind to erythrocytes in blood. The erythrocytes are then lysed when the complexes activate the complement system.

 

Chronic use of phenacetin is known to lead to analgesic nephropathy characterized by renal papillary necrosis.This is a condition which results in destruction of some or all of the renal papillae in the kidneys.

 

One notable death that can possibly be attributed to the use of this drug was that of the aviation pioneer Howard Hughes. He had been using phenacetin extensively for the treatment of chronic pain; it was stated during his autopsy that phenacetin use may have been the cause of his kidney failure.

 

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1. Rich experiences. Our company is a professional production leading factory inChinain pharmaceutical area of many years. Delivery areas of our products:US, UK, Canada, Australia, Brazil, Russia, Portugal, Latvia, Switzerland, Iceland, Ukraine, Germany, France, Netherlands, Belgium, Peru, Sweden, New Zealand, the Czech Republic, Lithuania, Ireland, Tunisia, Mexico, Greece, Puerto Rico, Thailand, Israel and so on,and we have got very good feedback from our customers, we had established a long friendly relations.


2. Discreet package. The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also take into consideration.


3.Top quality. High quality guarenteed, once any problem is found, the package would be reshipped for you.


4. Security Shipping. Shipping by express (FedEx,UPS,DHL,EMS), by air.The most professional forwarder would be recommanded for you.


5. Delivery Quickly. We have stock, so we can delivery quickly at the very day when receive the payment.


6. Warm after sale service for you. Any of your question would be solved for the first as soon as possible. Adhering to the principle of customer first conviction.we will provide the best and the most sincere services as possible as we can.


7. High quality, best price, first-class service, high successful delivery rate. A discount would be given when you make a large order.

 

 

 


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