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Home>Products>Local Anaesthesia Drugs>Hydrochloride Lidocaine Local Anesthetic Cas 6108 05 0 Pain Killer White Powder

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  • Hydrochloride Lidocaine Local Anesthetic Cas 6108 05 0 Pain Killer White Powder
  • Hydrochloride Lidocaine Local Anesthetic Cas 6108 05 0 Pain Killer White Powder
  • Hydrochloride Lidocaine Local Anesthetic Cas 6108 05 0 Pain Killer White Powder
  • Hydrochloride Lidocaine Local Anesthetic Cas 6108 05 0 Pain Killer White Powder

Hydrochloride Lidocaine Local Anesthetic Cas 6108 05 0 Pain Killer White Powder

  • LSW
  • 6108-05-0

  • China
  • GMP, ISO9001, USP, KOSHER
  • 10 grams
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  • Wuhan Liantian Technology Co.,Ltd2020-07-10 09:46:19
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Product Details

Appearance: White powder Assay: over 99% Package: 25KG/fiber drum
CAS number: 6108-05-0 MF: C14H25ClN2O2 MW: 288.81

Product Description

Local Anaesthetic Lidocaine Hydrochloride CAS: 6108-05-0 as Pain Killer White Powder

Description:

Lidocaine Hydrochloride is the hydrochloride salt from of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. Lidocaine hydrochloride also exhibits class IB antiarrhythmic effects. The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability.

Basic information:

CAS No.6108-05-0
Chemical Name:Lidocaine hydrochloride
Synonymsdolicaine;LINOCAINE HCL;Lidocaine HCl USP;Linocaine hydrochlor;LIDOCAINE HCL HYDRATE;-N-(2,6-dimethylphenyl);LINOCAINE HYDROCHLORIDE;LidocaineHclLidocaineHclBp;Linocaine hydrochloride hydrate;Lidocaine Hydrochloride hydrate
CBNumber:CB4486868
Molecular Formula: C14H25ClN2O2
Formula Weight: 288.81
Melting point: 75-79℃
solubility H2O: soluble
Form:solid
Color:white
Water Solubility:Soluble in water (50 mg/ml), chloroform, ethanol, and benzene. Insoluble in diethyl ether.

COA:

Product name Lidocaine hydrochloride
CAS No. 73-78-9 Outer Packing 25KG/Drum
Production date 2016-10-22 Shelf life 2021-10-21
Standard adopted EP8.5
Items of analysis Specification Results
Appearance White crystalline powder White crystalline powder
PH 4.64 4.5-5.5
residue on ignition ≤0.1% 0.05%
Water 5.0%-7.0% 6.43%
Heavy metal <5ppm ≤5ppm
residual solvent methyl alcohol≤0.5% Methanol ≤0.5% Methylbenzene ≤0.089% Toluene ≤0.089 0.068% 0.002%
Related substance Impurity A≤0.01% Unknown single impurity≤0.1% Not detected 0.01%
Assay 97.5%-101.0%(*) 99.86%
Conclusion Qualified

Medical uses:

Local numbing agent

The efficacy profile of lidocaine as a local anaesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anaesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for spinal and epidural anaesthesias; lidocaine, though, has the advantage of a rapid onset of action. Adrenaline vasoconstricts arteries, reducing bleeding and also delays the resorption of lidocaine, almost doubling the duration of anaesthesia.

Lidocaine is one of the most commonly used local anaesthetics in dentistry. It can be administered in multiple ways, most often as a nerve block or infiltration- depending on the type of treatment carried out and the area of the mouth worked on.

For surface anaesthesia, several formulations can be used for endoscopies, before intubations, etc. Buffering the pH of lidocaine makes local numbing less painful.Lidocaine drops can be used on the eyes for short ophthalmic procedures. There is tentative evidence for topical lidocaine for neuropathic pain and skin graft donor site pain.As a local numbing agent, it is used for the treatment of premature ejaculation.

Heart arrhythmia:

Lidocaine is also the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion, or cardiac catheterization) if amiodarone is not available or contraindicated. Lidocaine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine preventative dose is no longer recommended after a myocardial infarction as the overall benefit is not convincing.

Product List:

Product name CAS NO. Product name CAS NO.
Benzocaine 94-09-7 Procaine 59-46-1
Dapoxetine Hydrochloride 129938-20-1 Tetracaine HCl 136-47-0
Clobetasol Propionate 25122-46-7 L-Thyroxine 51-48-9
Finasteride 98319-26-7 Dydrogesterone 152-62-5
Theophylline 58-55-9/ 5967-84-0 Valdecoxib 181695-72-7
Procaine HCl 51-05-8 Lidocaine HCl 73-78-9
Lidocaine 137-58-6 Benzocaine HCl 23239-88-5
Dapoxetine 119356-77-3 L-Epinephrine hydrochloride 55-31-2/ 329-63-5
Chloramphenicol 56-75-7/ 2787-09-9 Doxorubicin hydrochloride 25316-40-9
Omeprazole 73590-58-6/ 119141-89-8 Benzyl benzoate 120-51-4
Dutasteride 164656-23-9 Cyanocobalamin 68-19-9/18195-32-9/ 13408-78-1
Acetaminophen 103-90-2 Paromomycin 7542-37-2
Amikacin disulfate salt 39831-55-5/ 149022-22-0 Nitazoxanide 55981-09-4
Dexamethasone sodium phosphate 55203-24-2/ 312-93-6 Secnidazole 3366-95-8
Trestolone acetate 6157-87-5 Tinidazole 19387-91-8
Lincomycin hydrochloride 7179-49-9 Chlorhexidine Gluconate 18472-51-0
Clotrimazole 23593-75-1 1,3-dimethyl-pentylamine hydrochloride 105-41-9
1,3-Dimethylbutylamine hydrochloride 71776-70-7 4 amino-2-Methylpentane citrate(AMP Citrate) 71776-70-0

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