Antifungal Local Anaesthesia Drugs Voriconazole White Raw Powder CAS 137234-62-9

Antifungal drugs Voriconazole White Raw Powder CAS 137234-62-9

 

Basic information:

 

Chemical name: Voriconazole
MF: C16H14F3N5O
MW: 349.31
CAS: 137234-62-9
Appearance: white powder
Purity: over 99%

 

COA:

 

Product name Product name	Voriconazole
CAS No.	137234-62-9	Outer Packing	1KG
Production date	2016.04.04	Shelf life	2018.04.03
Standard adopted	USP36
Items of analysis	Specification	Results
Appearance	White or almost white crystalline powder	white crystalline powder
Identification	A.IR B.HPLC	Conforms
Impurity C	≤0.2%	0.03%
Impurity D	≤0.1%	ND
unknown Impurity	≤0.1%	ND
Total impurity	≤0.5%	0.03%
Voriconazole Relatated Compound B	≤0.2%	ND
Voriconazole Relatated Compound F	≤0.1%	ND
Water	≤0.4%	0.18%
Residue on ignition	≤0.1%	0.06%
Heavy metals	≤10ppm	Conforms
Assay(HPLC)	97.5-102%	99.7%
Conclusion	Qualified

 

Descriptions:

Voriconazole is used to treat serious fungal or yeast infections, such as aspergillosis (fungal infection in the lungs), candidemia (fungal infection in the blood), esophageal candidiasis (candida esophagitis), or other fungal infections (infections in the skin, stomach, kidney, bladder, or wounds). It may also be used to treat patients with serious fungal or yeast infections who cannot tolerate other types of treatment or do not respond to other types of treatment.

 

Medical uses:

 

Voriconazole is used to treat invasive aspergillosis and candidiasis and fungal infections caused by Scedosporium and Fusarium species, which may occur in immunocompromised patients, including people undergoing allogeneic bone marrow transplant (BMT), who have hematologic cancers or who undergo organ transplants.

It is also used to prevent fungal infection in people as they undergo BMT.

 

It is also the recommended treatment for the CNS fungal infections transmitted by epidural injection of contaminated steroids.

 

It can be taken by mouth or given in a doctors office or clinic by intravenous infusion.

 

How should this medicine be used?

 

Voriconazole comes as a tablet and a suspension (liquid) to take by mouth. It is usually taken every 12 hours on an empty stomach, at least 1 hour before or 1 hour after a meal. To help you remember to take voriconazole, take it at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take voriconazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

 

If you are taking voriconazole suspension, shake the closed bottle for about 10 seconds before each use to mix the medication evenly. Do not mix the suspension with any other medications, water, or any other liquid. Always use the measuring device that comes with your medication. You may not receive the correct amount of medication if you use a household spoon to measure your dose.

At the beginning of your treatment, you may receive voriconazole by intravenous (into a vein) injection. When you begin taking voriconazole by mouth, your doctor may start you on a low dose and increase your dose if your condition does not improve. Your doctor also may decrease your dose if you experience side effects from voriconazole.

 

The length of your treatment depends on your general health, the type of infection you have, and how well you respond to the medication. Continue to take voriconazole even if you feel well. Do not stop taking voriconazole without talking to your doctor.

 

Dose & Delivery:

 

Oral, intravenous and ocular preparations of voriconazole are available. For intravenous usage a loading dose of 6mg/Kg twice at 12 hour intervals is recommended for life threatening infections in adults, followed by 4mg/Kg twice daily. The dose in children should be 7mg/Kg twice daily intravenously although very young children may require proportionately larger doses, because of rapid clearance. If drug-monitoring facilities are available the dose can be altered on the basis of blood levels. Bioavailability is nearly 100% so oral dosing can be relied upon, which is usually 200mg twice daily. Lower treatment doses should be given to adults weighing less than 40Kg, elderly people and any with prior liver disease to minimise the chance of high levels and toxicity. Dose increases result in disproportionate increase in drug exposure in adults, but not children, because the pharmacokinetics of voriconazole is not linear in adults.

 

Our Advantages:

 

1. Good reputation:
Our company is a leading chemical company in China, and has more than 16 years history. We have over 10 branch offices, all enjoy good reputation from worldwide customers.

 

2. High Quality&low price
All of our products have top quality and high purity, since we are the factory, our price is competitive.

 

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We have mutiple payment methods, T/T, Western Unoin, MoneyGram, and Bitcoin for your convenience.

 

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In order to better serve our customers, we are preparing mass stock in our warehouse, we can always ship your parcel within 24 hours.

 

5. High customs clearance pass rate.
Through 16 years hard work, we have accumulated rich exporting experience to USA, UK, France, Italy, Germany,Spain, Brail, korea, India and so on.We will use special ways to disguise the goods, 98% customs clearance rate is guaranteed, if the delivery is not successful, we will resend for free.

 

6. Warm After service.
If you have any problems about the goods, do no hesitate to contact us, we can provide 7/24 service.

 

How to proceed an order:

 

 

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