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Home>Products>Local Anaesthesia Drugs>CAS 148553-50-8 High Purity Local Anaesthesia Drugs White Pregabalin For Pain

CAS 148553-50-8 High Purity Local Anaesthesia Drugs White Pregabalin For Pain
- LSW
148553-50-8
- China
- GMP, ISO9001, USP, KOSHER
- 10 grams
- Negotiable
- Discreet disguised package or as required
- 3~7 working days
- Western Union, Moneygram, Bitcoin and Bank Wire Transfer
- 5000kg/week
-
Wuhan Liantian Technology Co.,Ltd2020-07-10 09:46:19
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Product Details
Appearance: | White powder | Synonyms: | Pregablin | Usage: | Local Anesthetic drug |
CAS number: | 148553-50-8 | MF: | C8H17NO2 | MW: | 159.23 |
Product Description
Pregabalin is a white to off-white, crystalline solid with a pKa1 of 4.2 and a pKa2 of 10.6. It is freely soluble in water and both basic and acidic aqueous solutions. The log of the partition coefficient (n-octanol/0.05M phosphate buffer) at pH 7.4 is 1.35.
The capsule shells contain gelatin and titanium dioxide. In addition, the orange capsule shells contain red iron oxide and the white capsule shells contain sodium lauryl sulfate and colloidal silicon dioxide. Colloidal silicon dioxide is a manufacturing aid that may or may not be present in the capsule shells. The imprinting ink contains shellac, black iron oxide, propylene glycol, and potassium hydroxide.
Items of analysis | Specification | Results |
Appearance | White or almost white powder | conforms |
Identification | IRandHPLC | conforms |
Loss on drying | ≤0.5% | 0.2% |
Specific Rotation | +10°~+12° | +10.77° |
Residue on ignition | ≤0.1% | 0.08% |
Heavy metals | ≤20ppm | conforms |
impurity C | ≤0.1% | conforms |
Any impurity | ≤0.1% | 0.044% |
Total impurity | ≤1.0% | 0.14% |
Assay(HPLC) | 98%-101% | 99.6% |
R-isomer | ≤0.15% | 0.033% |
Bromide cintent(Titrmetry) | ≤500ppm | 26ppm |
Ethanol | ≤5000ppm | conforms |
Isopropyl alcohol | ≤5000ppm | 142ppm |
≤5000ppm | conforms | |
≤60ppm | conforms | |
Conclusion | Qualified |
2. Pregabalin is a medication used to in the treatment of epilepsy, neuropathic pain, fibromyalgia and generalized anxiety disorder. Its use for epilepsy is as an add-on therapy for partial seizures with or without secondary generalization in adults.
3. Pregabalin is a structural analogue of the neurotransmitter GABA, consequently it belongs to the acid analogue class of antiepileptic drugs. Its a ion channel modulator that has analgesic, anticonvulsant, sedative, and anxiolytic properties. Pregabalin is a potent gabapentinoid and close analogue of GABOB, baclofen, and phenibut.
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