CAS 6108-05-0 White Local Anaesthesia Drugs Linocaine hydrochloride / Lidocaine

 

 

Lidocaine hydrochloride is an amide local anesthetic. Blood absorption or intravenous administration of the central nervous system has obvious excitement and inhibition of biphasic effects, and no excitement of excitement, plasma concentration is low, the emergence of analgesic and lethargy, pain threshold increased; with the dose plus Large, role or toxicity, sub-poisoning plasma concentration when the anti-convulsive effect.

 

This medication is used on the skin to stop itching and pain from certain skin conditions and to treat minor discomfort and itching caused by hemorrhoids and certain other problems of the genital/anal area . Some forms of this medication are also used to decrease discomfort or pain during certain medical procedures/exams Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes.

 

As with other local anaesthetics, lidocaine should be used with caution in patients with epilepsy, myasthenia gravis, congestive cardiac failure, bradycardia or respiratory depression, including where agents are known to interact with Lidocaine either to increase its availability or additive effects e.g. phenytoin or prolong its elimination e.g. hepatic or end renal insufficiency where the metabolites of Lidocaine may accumulate.

 

The effect of local anaesthetics may be reduced if the injection is made into an inflamed or infected area.

 

Intramuscular Lidocaine may increase creatinine phosphokinase concentrations which can interfere with the diagnosis of acute myocardial infarction. Lidocaine has been shown to be porphyrinogenic in animals and should be avoided in persons suffering from porphyria.

 

 

CAS No.6108-05-0

 

Chemical Name:Lidocaine hydrochloride

 

Synonymsdolicaine;LINOCAINE HCL;Lidocaine HCl USP;Linocaine hydrochlor;LIDOCAINE HCL HYDRATE;-N-(2,6-dimethylphenyl);LINOCAINE HYDROCHLORIDE;LidocaineHclLidocaineHclBp;Linocaine hydrochloride hydrate;Lidocaine Hydrochloride hydrate

 

CBNumber:CB4486868

 

Molecular Formula: C14H25ClN2O2

 

Molecular Weight: 288.81

 

Melting point: 75-79℃

 

solubility H2O: soluble

 

Form:solid

 

Color:white

 

Water Solubility:Soluble in water (50 mg/ml), chloroform, ethanol, and benzene. Insoluble in diethyl ether.

 

 

lidocaine hydrochloride is a local anesthetic indicated to provide the topical relief of pain and discomfort. Xylocaine Viscous 2% is available in generic form. Common side effects of Xylocaine Viscous 2% include application site reactions or numbness in places where the medicine is accidentally applied.

 

In its basic form, lidocaine hydrochloride is a white powder without smell and with a bitter taste that is used both in human and veterinary medicine. The drug is also known as lignocaine hydrochloride, and is used as a local anesthetic and to regulate certain medical problems related to heart rhythm. Injections of it are used to provide local anesthesia during various minor surgical procedures. It is also available in various topical preparations, such as gels, sprays, creams, and ointments that are usually applied to the skin or the mucous membranes.

 

When used for anesthetic purposes, lidocaine hydrochloride works by blocking certain functions of the nervous system, inhibiting the transmission of pain impulses from the treated area to the brain. It is a fast-acting form of local anesthesia that often starts to work within five minutes. The effects wear off in a relatively short time, often a couple of hours, because the drug is quickly metabolized by the liver.

 

 

Lidocaine hydrochloride has the characteristics of strong penetration, strong dissemination, rapid onset of action, twice the anesthetic potency and procaine, and a toxicity of 1. 5 minutes after treatment can occur anesthesia, anesthesia for 1 to 1.5 hours, 50% longer than procaine. After absorption can inhibit the central nervous system, and can inhibit ventricular autonomy, shortening refractory period, can be used to control ventricular tachycardia, premature ventricular contractions, ventricular tachycardia and ventricular fibrillation and other arrhythmia symptoms. Right heart disease or cardiac arrhythmia caused by cardiac glycosides are effective, supraventricular tachycardia is not effective. This product is fast, short duration, oral invalid, often as intravenous injection.

 

 

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