Wuhan Liantian Technology Co.,Ltd
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Home>Products>Local Anaesthesia Drugs>Local Anesthetics Dyclonine Hcl CAS 536-43-6 White Powder For Relieving Pain

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  • Local Anesthetics Dyclonine Hcl CAS 536-43-6 White Powder For Relieving Pain
  • Local Anesthetics Dyclonine Hcl CAS 536-43-6 White Powder For Relieving Pain
  • Local Anesthetics Dyclonine Hcl CAS 536-43-6 White Powder For Relieving Pain
  • Local Anesthetics Dyclonine Hcl CAS 536-43-6 White Powder For Relieving Pain

Local Anesthetics Dyclonine Hcl CAS 536-43-6 White Powder For Relieving Pain

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  • 536-43-6

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  • Wuhan Liantian Technology Co.,Ltd2020-07-10 09:46:19
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Product Details

MF: C18H28ClNO2 MW: 325.87 Purity: 99%
Appearance: White Crystalline Powder CAS number: 536-43-6 Usage: Local Anesthetics

Product Description

Local Anesthetics Dyclonine hcl CAS 536-43-6 White Powder for Relieving the Pain

Description:

Dyclonine Hydrochloride is the hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membranes permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.

Basic information:

Chemical name: Dyclonine hydrochloride
MF: C18H28ClNO2
MW: 325.87
CAS: 536-43-6
Appearance: white powder
Purity: over 99%

Application:

Dyclonine is an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membranes permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.


Pharmacology from NCIt


Dyclonine is only found in individuals that have used or taken this drug. It is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray. Dyclonine blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membranes permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.

History:

The product Sucrets was introduced in Baltimore, Maryland, by Sharp & Dohme in 1932.

In 1966 the Federal Trade Commission ordered Merck and Company to discontinue the false claims of germ-killing and pain-relieving properties for its Sucrets and Childrens Sucrets throat lozenges.In 1977, it was acquired by Beecham, later merging with SmithKline Beckman in 1989 to form SmithKline Beecham. By 1994 the brand switched from a metal container to a plastic container.SmithKline Beecham, after announcing a merger with GlaxoWellcome to form GlaxoSmithKline, sold the brand in 2000 to Insight Pharmaceuticals. In 2011, Sucrets reintroduced their product back into the familiar tin due to popular demand and nostalgia.

Our Advantages:

Rich experience Our company have a history of over 10 years and branch offices all around China.
Top quality All products are carefully tested and most of the purity can up to 99%, COA is available.
Competitive price We are the manufacture, so we have the most competitive price.
Safe packing Discreet package will be applied, or as you required.
Safe customs clearance Our customs clearance pass rate is above 99%.
Fast delivery We will delivery your parcel within 24 hours after payment.
Warm after service You can Contact us any time, we will try our best to offer you the best service.

How to proceed an order:

If you have any questions, please feel free to contact me.

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