Anti - Estrogen Oral Anabolic Steroids Clomiphene Citrate / Clomid 50-41-9

Anti-Estrogen Oral Anabolic Steroids Clomiphene Citrate / Clomid 50-41-9 for Treating Infertility

Clomiphene Citrate or Clomid is a powerfully effective anti-estrogen officially classified as a Selective Estrogen Receptor Modulator (SERM). In many ways, it is very similar to another popular SERM in Nolvadex (Tamoxifen Citrate). Clomid first gained worldwide attention in the early 1970s as a strong fertility aid and is still used for that purpose today. It is also one of the most commonly used SERMs by anabolic steroid users. No, it is not an anabolic steroid but can be used to combat estrogenic side effects sometimes caused by anabolic steroids. It can also be used as a Post Cycle Therapy (PCT) medication in order to stimulate suppressed testosterone production due to anabolic steroid use. PCT use of Clomid is the most common purpose and most beneficial point of use for the anabolic steroid user.

Quick Details:

Clomifene citrate
Another name: 2-4-[2-Chloro-1,2-diphenylethenyl]phenoxy-N,N-diethylethanamine citrate
CAS NO: 50-41-9
Structural formula: C26H28ClNO C6H8O7
Molecular weight: 598.11
Appearance: white or milky white crystalline powder
Standard: CP USP
Use: the goods to anti-estrogen fertility inducer, the objects in dysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug-induced amenorrhea and other gynecologic diseases

COA:

History:

A team at William S. Merrell Chemical Company led by Frank Palopoli synthesized clomifene in 1956; after its biological activity was confirmed a patent was filed and issued in November 1959. Scientists at Merrell had previously synthesized chlorotrianisene and ethamoxytriphetol.

Clinical studies were conducted under an Investigational New Drug Application; it was third drug for which an IND had been filed under the 1962 Kefauver Harris Amendment to the Federal Food, Drug, and Cosmetic Act that had been been passed in response to the thalidomide tragedy. It was approved for marketing in 1967 under the brand name Clomid. It was first used to treat cases of oligomenorrhea but was expanded to include treatment of anovulation when women undergoing treatment had higher than expected rates of pregnancy.

The drug is widely considered to have been a revolution in the treatment of female infertility, the beginning of the modern era of assisted reproductive technology, and the beginning of what in the words of Eli Y. Adashi, was "the onset of the US multiple births epidemic".

Application:

Clomifene citrate is useful in those who are infertile due to anovulation or oligoovulation.Evidence is lacking for the use of clomifene in those who are infertile without a known reason.In such cases, studies have observed a clinical pregnancy rate 5.6% per cycle with clomifene treatment vs. 1.3%-4.2% per cycle without treatment.

Clomifene citrate has also been used with other assisted reproductive technology to increase success rates of these other modalities.

As for toxicity and side effects, Clomid is considered a very safe drug. Bodybuilders seldom report any problems, but listed possible side effects do include hot flashes, nausea, dizziness, headaches and temporarily blurred vision.

Such side effects usually only appear in females however, as they feel the effects of estrogen manipulation much more readily than men. While female athletes can clearly gain some benefit from this substance, estrogen manipulation is probably not the most comfortable way to go about cutting up.

Should it still be used for such purposed and side effects do become pronounced, the drug of course is to be discontinued and (at least) a break taken from it.

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Anti - Estrogen Oral Anabolic Steroids Clomiphene Citrate / Clomid 50-41-9 Images