Sildenafil Viagra Powder Sex Enhancing Drugs CAS 139755-83-2 Treating ED

Sex Enhancing Drugs Sildenafil, Viagra White Powder CAS: 139755-83-2 for Treating ED

Description:

Sildenafil is a vasoactive agent used to treat erectile dysfunction and reduce symptoms in patients with pulmonary arterial hypertension (PAH). Sildenafil elevates levels of the second messenger, cGMP, by inhibiting its breakdown via phosphodiesterase type 5 (PDE5). PDE5 is found in particularly high concentrations in the corpus cavernosum, erectile tissue of the penis. It is also found in the retina and vascular endothelium. Increased cGMP results in vasodilation which facilitates generation and maintenance of an erection. The vasodilatory effects of sildenafil also help reduce symptoms of PAH.

Basic Information:

Chemical name: SILDENAFIL
MF: C22H30N6O4S
MW: 474.58
CAS: 139755-83-2
Appearance: white powder
Usage: Male enhancement drug.

COA:

PRODUCT		Sildenafil citrate USP37
Date of analaysis			01/09/2015			Batch No		SDF:0915042
Dispatch Quality:500KG						A.R.NO		F.P.15/0095
Mfg Date:Semptember,2015						Mfg.quality		681.50KG
Retest Date						August ,2020
S.NO	TEST PARAMETER			SPECIFICATION			RESULT
1.	Description			White or almost white,slightly hygroscopic crystalline powder			almost white,slightly hygroscopic crystalline powder
2.	Solubility			Slightly soluble in water and in methanol ,practically insoluble in hexane			Slightly soluble in water and in methanol ,practically insoluble in hexane
3.	Identification by IR			The infrared absorption spectrum of the potassium bromide dispersion of the sample preparation should be exhibit maxima only at the same wave numbers as that of Sildenafil citrate working standard/reference standard			The infrared absorption spectrum of the potassium bromide dispersion of the sample preparation should be exhibit maxima only at the same wave numbers as that of Sildenafil citrate working standard/reference standard
4.	Organic Impurities by HPLC(%,w/w)
	Related compound-A			Not more than 0.3			BDL
	Andy other unspecified individual impurity			Not more than 0.10			BDL
	Total unspecified impurities			Not more than 0.3			BDL
5.	Limit of imidazole by TLC			Not more than 0.1			Less than 0.1
6.	Whate content by KF(%,w/m)			Not more than 2.0(as per costomer spec)			1.11
7.	Residue on ignition (%,w/m)			Not more than 0.1			0.06
8.0	Heavy metals (ppm)			Not more than 20			Less than 20
8.	Heavy by HPLC(anhydrous and solvent free basis (%,w/m)			Not less than 98.0 and not more than 102			100.1
9.	Residule solvent by GC (PPM)
	Acctone				Not more than 5000		20
	Ethyl acetate				Not more than 5000		ND
	Methylene chloride				Not more than 600		ND
	Toluene				Not more than 890		ND
Remarks:the product conforms to the USP37 Specifications The product is APPROVED. Note:BDL-below Disregard Limit ND-Not Detected

Why is this medication prescribed?

Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Revatio) is used to improve the ability to exercise in adults with pulmonary arterial hypertension (PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). Children should not usually take sildenafil, but in some cases, a doctor may decide that sildenafil (Revatio) is the best medication to treat a childs condition. Sildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily.

If you are taking sildenafil to treat erectile dysfunction, you should know that it does not cure erectile dysfunction or increase sexual desire. Sildenafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV).

Medical uses:

Four 100 mg diamond-shaped tablets of branded Viagra

Sexual dysfunction

The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now one of the standard treatments for erectile dysfunction, including for men with diabetes mellitus.

Antidepressant-associated sexual dysfunction

Tentative evidence suggests that sildenafil may help men who experience antidepressant-induced erectile dysfunction.

Pulmonary hypertension

While sildenafil improves some markers of disease in people with pulmonary arterial hypertension, it does not appear to affect the risk of death or serious side effects as of 2014.

Altitude sickness

Sildenafil appears to improve some risk factors for high-altitude pulmonary edema but it is unclear whether or not it affects the rate of the condition itself as of 2008.

Raynauds phenomenon

Sildenafil and other PDE5 inhibitors have moderate efficacy for treating secondary Raynauds phenomenon.

What is the dosage for sildenafil?

The usual recommended dose is 25 to 100 mg 1 hour before sexual activity.

The maximum dose is 100 mg daily.

The elderly (over 65 years of age) should start at 25 mg before sexual activity.

Sildenafil is rapidly absorbed. Maximum observed plasma concentrations are reached within 30 to 120 minutes (median 60 minutes) of oral dosing in the fasted state. When sildenafil is taken with a high fat meal, the rate of absorption is reduced, with an average delay in the time to maximal concentration of 1 hour.

Medical uses:

Four 100 mg diamond-shaped tablets of branded Viagra

Sexual dysfunction

The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now one of the standard treatments for erectile dysfunction, including for men with diabetes mellitus.

Antidepressant-associated sexual dysfunction

Tentative evidence suggests that sildenafil may help men who experience antidepressant-induced erectile dysfunction.

Pulmonary hypertension

While sildenafil improves some markers of disease in people with pulmonary arterial hypertension, it does not appear to affect the risk of death or serious side effects as of 2014.

Altitude sickness

Sildenafil appears to improve some risk factors for high-altitude pulmonary edema but it is unclear whether or not it affects the rate of the condition itself as of 2008.

Raynauds phenomenon

Sildenafil and other PDE5 inhibitors have moderate efficacy for treating secondary Raynauds phenomenon.

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